Other forms of programmed cell death include anoikis almost identical to apoptosis except in its induction cornification a form of cell death exclusive to the eyes excitotoxicity ferroptosis an iron dependent form of cell death and wallerian degeneration necroptosis is a programmed form of necrosis or inflammatory cell death. Other members of the bcl 2 family are not death inhibitors but instead promote procaspase activation and cell death some of these apoptosis promoters such as bad function by binding to and inactivating the death inhibiting members of the family whereas others like bax and bak stimulate the release of cytochrome c from mitochondria. A million cells in our bodies die every second they commit suicide by activating a process called apoptosis or other forms of programmed cell death these mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes the immune system and cancer. Apoptosis definition is a genetically directed process of cell self destruction that is marked by the fragmentation of nuclear dna is activated either by the presence of a stimulus or removal of a suppressing agent or stimulus is a normal physiological process eliminating dna damaged superfluous or unwanted cells and when halted as by gene mutation may result in uncontrolled cell
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